lncRNome: a comprehensive knowledgebase of human long noncoding RNAs

Abstract

The advent of high-throughput genome scale technologies has enabled us to unravel a large amount of the previously unknown transcriptionally active regions of the genome. Recent genome-wide studies have provided annotations of a large repertoire of various classes of non-coding transcripts. Long noncoding RNAs form a major proportion of these novel annotated noncoding transcripts, and presently known to be involved in a number of functionally distinct biological processes. Over 18,000 transcripts are presently annotated as long noncoding RNA, and encompass previously annotated classes of noncoding transcripts including lincRNA, antisense RNA and processed pseudogenes. There is a significant gap in the resources providing a stable annotation, cros-referencing and biologically relevant information. lncRNome has been envisioned with the aim of filling this gap by integrating annotations, on a wide variety of biologically significant information into a comprehensive knowledgebase. To the best of our knowledge, lncRNome is the largest and most comprehensive resource for long noncoding RNAs and is available at URL: http://genome.igib.res.in/lncRNome


Bhartiya D,Pal K, Ghosh S, Kapoor S, Jalali S, Panwar B, Jain S, Sati S, Sengupta S, Sachidanandan C, Raghava GPS, Sivasubbu S and Scaria V*
lncRNome: a comprehensive knowledgebase of human long noncoding RNAs
Database (2013) Accepted