Forthcoming talks

  • These are a tentative list of forthcoming invited talks. The talk title, content and attendance are likely to change. [List of forthcoming talks]
  • Genomics in Clinical Medicine | Thiruvananthapuram and Kochi Genomic technologies have been progressing rapidly in the recent years. Many of these advances have accelerated our understanding of human disease biology with implications in better molecular characterization of diseases ...
    Posted Dec 26, 2018, 2:13 AM by Vinod Scaria
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Translational Genomics

Translational Genomics is an Open Access journal dedicated to publishing scientific advances in genomics and other omics technologies and its application in Medicine.
Editors-in-Chief: Vinod Scaria & Sridhar Sivasubbu
Inaugural Issue: 2019 
Clinical Genomics / Precision Medicine Initiatives India, South-East Asia and Middle East
Precision Medicine
Mycobacterium tuberculosis genomes
Zebrafish Wild-type Strain [Data/Resources] 

Genomics for Precision Medicine in India

http://guardian.meragenome.com
CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB) has initiated a unique programme on this front, pioneering the application of Genomics for Public Health (IndiGen) in India. The Genomics for Understanding Rare Disease, India Alliance Network (GUaRDIAN) is a large-scale collaborative network of clinicians from around India trying to integrate genomics in clinical practice, with the a singular focus to elucidate the genetic structure of Rare Genetic Diseases in India. Omics for Precise Therapeutic Interventions Minimizing Adverse Events (OPTIMA) is a collaborative initiative towards implementing pharmacogenetics in Clinics.

Lab in News

  • 5-year-old ‘butterfly’ boy at PGI for treatment Shimona Kanwar| TNN | Updated: Apr 12, 2018, 11:13 ISTFull text: https://timesofindia.indiatimes.com/city/chandigarh/5-year-old-butterfly-boy-at-pgi-for-treatment/articleshow/63720834.cms ...
    Posted Apr 13, 2018, 10:29 PM by Vinod Scaria
  • Interpretation of a malady: how scientists zeroed in on one family's rare and crippling disease The poignant story of an Agra family, where six children have the Nalband mutation. Jacob Koshy reports on how a group of scientists linked it to a rare and crippling ...
    Posted Apr 21, 2017, 11:03 PM by Vinod Scaria
  • The year of Personal Genomics (The Hindu, Jan01,2017) The conversation around personal genomics amplified in 2016, as did the range of diagnostic options - by Jacob KoshyRead Full-text here: http://www.thehindu.com/sci-tech/health/The ...
    Posted Jan 4, 2017, 6:47 AM by Vinod Scaria
  • Qatar exome study: An advancement in precision medicine (Nature Middle East) By Louise Sarant Scientists look at Qataris' exome sequences to anticipate response to two common blood-thinnersThe study, by a team from the Delhi-based CSIR Institute of Genomics ...
    Posted Oct 4, 2016, 2:30 AM by Vinod Scaria
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Recent Publications
[Complete list of publications are available here]

Sharma D, Sehgal P, Mathew S, Vellarikkal SK, Singh AR, Kapoor S, Jayarajan R, Scaria V* & Sivasubbu S* 
A genome-wide map of circular RNAs in adult zebrafish
Scientific Reports (2019) 9, 3432

Thottath J, Vellarikkal SK, Jayarajan R, Verma A, Manamel M, Singh A, Rajendran VR, Sivasubbu S and Scaria V
A novel cathepsin D mutation in 2 siblings with late infantile neuronal ceroid lipofuscinosis
Neurol Genet 5:e302 (2019)

Advances in Genetics (Academic Press) (2019) https://doi.org/10.1016/bs.adgen.2018.09.001

Sharma D, Sehgal S, Hariprakash J, Sivasubbu S, and Scaria V*
Methods for Annotation and Validation of Circular RNAs from RNAseq Data
Methods Mol Biol. (2019) Accepted

Mathew S, Sivadas A, Sehgal P, Kaushik K, Vellarikkal SK, Scaria V, and Sivasubbu SMethods Mol Biol. (2019) Accepted

Sivadas A, Scaria V*
Pharmacogenomic survey of Qatari populations using whole genome and exome sequences
The Pharmacogenomics Journal. (2018) Accepted doi:10.1038/s41397-018-0022-8

Hariprakash JM, Vellarikkal SK, Verma A, Ranawat AS, Jayarajan R, Ravi R, Kumar A, Dixit V, Sivadas A, Kashyap AK, Senthivel V, Sehgal P, Mahadevan V, Scaria V,* and Sivasubbu S*
SAGE: a comprehensive resource of genetic variants integrating South Asian whole genomes and exomes
Database (2018) Vol. 2018: article ID bay080; doi:10.1093/database/bay080

Vellarikkal SK, Jayarajan R, Verma A, Ravi R, Senthilvel V, Kumar A, Saini L, Gulati S, Lal M, Mathur A, Chhetri MK, Faruq M, Scaria V, Sivasubbu S
Clinical Genetics (2018) Accepted

Molecular Genetics and Genomics (2018) Accepted

Yenamandra VK, Vellarikkal SK, Chowdhury MR, Jayarajan R, Verma A, Scaria V, Sivasubbu S, Basu Ray S, Dinda AK, Kabra M, Sharma VK, Sethuraman G.
Genotype-Phenotype Correlations of Dystrophic Epidermolysis Bullosa in India: Experience from a Tertiary Care Centre.
Acta Derm Venereol. (2018) Mar 27. doi: 10.2340/00015555-2929. [Epub ahead of print]

(*as communicating/co-communicating author)