Forthcoming talks

  • These are a tentative list of forthcoming invited talks. The talk title, content and attendance are likely to change. [List of forthcoming talks]
  • Advances in Genetic Diagnosis of Neurological Disorders (Jointly organized by MMM-CGSR & CSIR-IGIB ) Jointly organized by  MMM-CGSR & CSIR-IGIB September 7-9, 2018 MADRAS MEDICAL MISSION, CHENNAIFor more Information, please contactDr. Bibhas KarCenter for Genetic Studies & ResearchThe Madras ...
    Posted Jun 13, 2018, 2:49 AM by Vinod Scaria
Showing posts 1 - 1 of 11. View more »

Translational Genomics

Translational Genomics is an Open Access journal dedicated to publishing scientific advances in genomics and other omics technologies and its application in Medicine.
Editors-in-Chief: Vinod Scaria & Sridhar Sivasubbu
Inaugural Issue: 2018 
Clinical Genomics / Precision Medicine Initiatives India, South-East Asia and Middle East
Precision Medicine
Mycobacterium tuberculosis genomes
Zebrafish Wild-type Strain [Data/Resources] 
(in collaboration with Dr. Sridhar Sivasubbu, IGIB)
Pan Asian Population Genomics Initiative (PAPGI)

Genomics for Precision Medicine in India

http://guardian.meragenome.com
CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB) has initiated a unique programme on this front, pioneering the application of Genomics for Precision Medicine in India.
The Genomics for Understanding Rare Disease, India Alliance Network (GUaRDIAN) is a large-scale collaborative network of clinicians from around India trying to integrate genomics in clinical practice, with the a singular focus to elucidate the genetic structure of Rare Genetic Diseases in India. Omics for Precise Therapeutic Interventions Minimizing Adverse Events (OPTIMA) is a collaborative initiative towards implementing pharmacogenetics in Clinics.

Lab in News

  • 5-year-old ‘butterfly’ boy at PGI for treatment Shimona Kanwar| TNN | Updated: Apr 12, 2018, 11:13 ISTFull text: https://timesofindia.indiatimes.com/city/chandigarh/5-year-old-butterfly-boy-at-pgi-for-treatment/articleshow/63720834.cms ...
    Posted Apr 13, 2018, 10:29 PM by Vinod Scaria
  • Interpretation of a malady: how scientists zeroed in on one family's rare and crippling disease The poignant story of an Agra family, where six children have the Nalband mutation. Jacob Koshy reports on how a group of scientists linked it to a rare and crippling ...
    Posted Apr 21, 2017, 11:03 PM by Vinod Scaria
  • The year of Personal Genomics (The Hindu, Jan01,2017) The conversation around personal genomics amplified in 2016, as did the range of diagnostic options - by Jacob KoshyRead Full-text here: http://www.thehindu.com/sci-tech/health/The ...
    Posted Jan 4, 2017, 6:47 AM by Vinod Scaria
  • Qatar exome study: An advancement in precision medicine (Nature Middle East) By Louise Sarant Scientists look at Qataris' exome sequences to anticipate response to two common blood-thinnersThe study, by a team from the Delhi-based CSIR Institute of Genomics ...
    Posted Oct 4, 2016, 2:30 AM by Vinod Scaria
Showing posts 1 - 4 of 15. View more »
Recent Publications
[Complete list of publications are available here]

Sivadas A, Scaria V
Pharmacogenomic survey of Qatari populations using whole genome and exome sequences
The Pharmacogenomics Journal. (2018) Accepted doi:10.1038/s41397-018-0022-8

Hariprakash JM, Vellarikkal SK, Verma A, Ranawat AS, Jayarajan R, Ravi R, Kumar A, Dixit V, Sivadas A, Kashyap AK, Senthivel V, Sehgal P, Mahadevan V, Scaria V,* and Sivasubbu S*
SAGE: a comprehensive resource of genetic variants integrating South Asian whole genomes and exomes
Database (2018) Vol. 2018: article ID bay080; doi:10.1093/database/bay080

Vellarikkal SK, Jayarajan R, Verma A, Ravi R, Senthilvel V, Kumar A, Saini L, Gulati S, Lal M, Mathur A, Chhetri MK, Faruq M, Scaria V, Sivasubbu S
A founder mutation MLC1 c.736delA associated with megalencephalic leukoencephalopathy with subcortical cysts-1 in north Indian kindred 
Clinical Genetics (2018) Accepted

Jain, A, Gandhi S, Koshy R, Scaria V*
Incidental and clinically actionable genetic variants in 1005 whole exomes and genomes from Qatar
Molecular Genetics and Genomics (2018) Accepted

Yenamandra VK, Vellarikkal SK, Chowdhury MR, Jayarajan R, Verma A, Scaria V, Sivasubbu S, Basu Ray S, Dinda AK, Kabra M, Sharma VK, Sethuraman G.
Genotype-Phenotype Correlations of Dystrophic Epidermolysis Bullosa in India: Experience from a Tertiary Care Centre.
Acta Derm Venereol. (2018) Mar 27. doi: 10.2340/00015555-2929. [Epub ahead of print]

Kaushik K, Sivadas A, Vellarikkal SK, Verma A, Jayarajan R, Pandey S, Sethi T, Maiti, Scaria V, Sivasubbu S
RNA secondary structure profiling in zebrafish reveals unique regulatory features
BMC Genomics (2018) Accepted

Sabharwal A, Sharma D, Vellarikkal SK, Jayarajan R, Verma R, Senthivel V, Scaria V, Sivasubbu S
Organellar transcriptome sequencing reveals mitochondrial localization of nuclear encoded transcripts 
Mitochondrion (2018) Accepted

Hariprakash JM, Vellarikkal SK, Keechilat P, Verma A, Jayarajan R, Dixit V, Ravi R, Senthivel V, Kumar A, Sehgal P, Aradhana, Sonakar AK, Ambawat S, Giri AK, Philip A, Sivadas A, Faruq M, Bharadwaj D, Sivasubbu S, Scaria V
Pharmacogenetic landscape of DPYD variants in South Asian populations by integration of genome-scale data
Pharmacogenomics (2017) Accepted

Koshy R, Sivadas A, Scaria V.
Genetic epidemiology of Familial Mediterranean Fever through integrative analysis of whole genome and exome sequences from Middle East and North Africa
Clinical Genetics (2017) Accepted

Koshy R, Ranawat A, Scaria V.
al mena - a comprehensive resource of human genetic variants integrating genomes and exomes from Arab, Middle Eastern and North African populations.
Journal of Human Genetics (2017) Accepted

(*as communicating/co-communicating author)