Research

Computational Biology of noncoding functional RNAs · 
Computational approaches towards unraveling the repertoire of noncoding functional RNAs in vertebrate genomes.
· Function and regulation of long noncoding RNAs (lncRNAs)
· Function and regulation of circular RNAs (circRNAs)

Genome Informatics and organisation of information in genomes 
· Integrative Assembly and Annotation of Whole Genomes: We recently announced the whole-genomes of Zebrafish Wild-type strain genome. 

Integrative analysis and Community Annotation of Genomes and large Genomics data-sets. 
· Data Integration for Genomics Analyses
· Community Infrastructure (Web 2.0 applications) and Semantic Web for Genome Annotation and Collaborative research. We recently are undertaking the Gene Ontology annotation of Mycobacterium tuberculosis H37Rv involving a large number of volunteers and Web 2.0 applications, under the OSDD Initiative. More about this













Clinical Genomics/Precision Medicine
· Population scale genomics and Precision Medicine. See details on first Indian 
· Genomic Data, Standards and tools for Translational medicine (more about OpenPGx) Genome. First Malaysian Personal Genome and Arab Genomes
Indian Genome / Personal Genome Sequencing @ CSIR-IGIB

Genomics of Pathogens and Microbes
· Hologenomics for pathogen identification in epidemic settings 
· Understanding genome dynamics and variation in pathogen genomes 

Mitochondrial Genomics and Epigenomics
· Human mitochondrial epigenome
· Genomics approaches for Mitochondrial Disease diagnosis, screening and prevention
· Genomics approaches to understand mitochondrial function and biology

Computational Chemical Biology

Lab in News

  • Selected News reports on research we do
  • 5-year-old ‘butterfly’ boy at PGI for treatment Shimona Kanwar| TNN | Updated: Apr 12, 2018, 11:13 ISTFull text: https://timesofindia.indiatimes.com/city/chandigarh/5-year-old-butterfly-boy-at-pgi-for-treatment/articleshow/63720834.cms ...
    Posted Apr 13, 2018, 10:29 PM by Vinod Scaria
  • Interpretation of a malady: how scientists zeroed in on one family's rare and crippling disease The poignant story of an Agra family, where six children have the Nalband mutation. Jacob Koshy reports on how a group of scientists linked it to a rare and crippling ...
    Posted Apr 21, 2017, 11:03 PM by Vinod Scaria
  • The year of Personal Genomics (The Hindu, Jan01,2017) The conversation around personal genomics amplified in 2016, as did the range of diagnostic options - by Jacob KoshyRead Full-text here: http://www.thehindu.com/sci-tech/health/The ...
    Posted Jan 4, 2017, 6:47 AM by Vinod Scaria
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