Research

Computational Biology of noncoding functional RNAs · 
Computational approaches towards unraveling the repertoire of noncoding functional RNAs in vertebrate genomes.
· Function and regulation of long noncoding RNAs (lncRNAs)
· Function and regulation of circular RNAs (circRNAs)

Genome Informatics and organisation of information in genomes 
· Integrative Assembly and Annotation of Whole Genomes: We recently announced the whole-genomes of Zebrafish Wild-type strain genome. 

Integrative analysis and Community Annotation of Genomes and large Genomics data-sets. 
· Data Integration for Genomics Analyses
· Community Infrastructure (Web 2.0 applications) and Semantic Web for Genome Annotation and Collaborative research. We recently are undertaking the Gene Ontology annotation of Mycobacterium tuberculosis H37Rv involving a large number of volunteers and Web 2.0 applications, under the OSDD Initiative. More about this













Clinical Genomics/Precision Medicine
· Population scale genomics and Precision Medicine. See details on first Indian 
· Genomic Data, Standards and tools for Translational medicine (more about OpenPGx) Genome. First Malaysian Personal Genome and Arab Genomes . IndiGen Population genomes
Indian Genome / Personal Genome Sequencing @ CSIR-IGIB

Genomics of Pathogens and Microbes
· Hologenomics for pathogen identification in epidemic settings 
· Understanding genome dynamics and variation in pathogen genomes 

Mitochondrial Genomics and Epigenomics
· Human mitochondrial epigenome
· Genomics approaches for Mitochondrial Disease diagnosis, screening and prevention
· Genomics approaches to understand mitochondrial function and biology

Computational Chemical Biology

Lab in News

  • Selected News reports on research we do
  • COVID-19 Response: Young Scientists Are Among India’s Unsung Heroes After the pandemic began, Vinod Scaria’s laboratory at CSIR-IGIB initiated a few projects to analyse the virus’s genetic data as obtained from different parts of the country ...
    Posted Jun 28, 2020, 9:42 PM by Vinod Scaria
  • The Gene Business Technology advances in gene sequencing are creating new opportunities for enterprises in healthcare and other sectors - writes Joe Mathew in Business TodayAre you genetically predisposed to some diseases? Do ...
    Posted Mar 9, 2020, 2:34 AM by Vinod Scaria
  • Genome sequencing by CSIR to help in Precision Medicine in India The Council for Scientific and Industrial Research has sequenced the entire genomes of 1008 Indians in six months, under a mission that was aimed at demonstrating capability and scalability of ...
    Posted Oct 31, 2019, 12:24 AM by Vinod Scaria
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